BMC Evolutionary Biology

official impact factor 3.70

Open Access Highly Access Research article

Conservation of intron and intein insertion sites: implications for life histories of parasitic genetic elements

Kristen S Swithers1, Alireza G Senejani1,2, Gregory P Fournier1 and J Peter Gogarten1*

Author Affiliations

1 Department of Molecular and Cell Biology University of Connecticut, 91 North Eagleville Road Storrs CT 06269-3125 USA

2 Current address: Departments of Therapeutic Radiology and Genetics, Yale University School of Medicine, PO Box 208040 New Haven, CT 06520-8040 USA

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BMC Evolutionary Biology 2009, 9:303 doi:10.1186/1471-2148-9-303

Published: 31 December 2009

Additional files

Additional file 1:

Table of p-values and alignment profiles for additional 37 intein, group I or group II host proteins. Arrows point to intron or intein positions. Blue dots indicate intein positions, green dots group I intron positions, and orange dots group II intron positions.

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Open Data

Additional file 2:

List of Introns found in Cytochrome C oxidase subunit I. The list contains all introns from species for which at least one of their cox1 gene introns were BLAST hits when introns from Podospora anserina (X55026) and Saccharomyces cerevisiae (V00694) cox1 genes were used as query sequences.

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Open Data

Additional file 3:

Accession numbers for sequences used in protein alignment. Lists of accession numbers for each protein used for each conservation profile.

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Additional file 4:

Perl scripts used to calculate the conservation profiles. Perl scripts used to calculate conservation profiles.

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Open Data