  Research articleEmergence, development and diversification of the TGF-β signalling pathway within the animal kingdomLukasz Huminiecki1 1 Ludwig Institute for Cancer Research, Uppsala University, Uppsala, Sweden 2 Computational Genomics, Institute of Agrobiotechnology, Thessaloniki, Greece
BMC Evolutionary Biology 2009, 9:28doi:10.1186/1471-2148-9-28
Additional filesAdditional file 1: Figure S1. Smad phylogenomic tree (rooted on time). View in magnification (at least 200%), in a pdf viewer such as Acrobat Reader, Adobe Acrobat or kpdf. Format: PDF Size: 310KB Download file This file can be viewed with: Adobe Acrobat Reader Additional file 2: Figure S2. Receptor phylogenomic tree (rooted on time). View in magnification (at least 200%), in a pdf viewer such as Acrobat Reader, Adobe Acrobat or kpdf. Format: PDF Size: 365KB Download file This file can be viewed with: Adobe Acrobat Reader Additional file 3: Figure S3. Bayesian phylogenetic tree demonstrates that the familiar pattern of four Smads grouped into three functional classes can be also observed in Lophotrochozoans. The tree is rooted using Dad. Accessions given are JGI gene model numbers. Format: PDF Size: 162KB Download file This file can be viewed with: Adobe Acrobat Reader Additional file 4: Figure S4. Two R-Smads (AqSmad1 and AqSmad2) have been detected in Amphimedon genomic traces. The tree is rooted using Dad. Format: PDF Size: 141KB Download file This file can be viewed with: Adobe Acrobat Reader Additional file 5: Sequences. All sequences and alignments are provided in the supplementary archive. Format: ZIP Size: 2.8MB Download file |
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