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Open AccessResearch article

Phylogenetic analysis of the SAP30 family of transcriptional regulators reveals functional divergence in the domain that binds the nuclear matrix

Keijo M Viiri email, Taisto YK Heinonen email, Markku Mäki email and Olli Lohi email

Paediatric Research Centre, University of Tampere Medical School and Tampere University Hospital, 33520 Tampere, Finland

author email corresponding author email

BMC Evolutionary Biology 2009, 9:149doi:10.1186/1471-2148-9-149

Published: 30 June 2009

Additional files

Additional file 1:

Clustal V alignment of the SAP30 family members in plants.

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Additional file 2:

Clustal V alignment of the SAP30 family members in animals. The arrows indicate the zinc coordinating residues. Red arrows and green boxes indicate the locations of secondary structural elements as deduced from the solution structure [13].

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Additional file 3:

Clustal W alignment of the SAP30 family members in yeasts.

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Additional file 4:

Maximum parsimony phylogenetic tree of the SAP30 protein family. The statistical reliability of the inferred tree topologies was assessed by the jackknife test. The jackknife values from 1000 data sets are shown at each node. The monophyletic tetrapodan/sarcopterygian SAP30 group is shaded.

Format: PDF Size: 40KB Download file

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Additional file 5:

Maximum likelihood phylogenetic tree of the SAP30 protein family. The statistical reliability of the inferred tree topologies was assessed by the jackknife test. The jackknife values from 100 data sets are shown at each node. The monophyletic tetrapodan/sarcopterygian SAP30 group is shaded.

Format: PDF Size: 45KB Download file

This file can be viewed with: Adobe Acrobat Reader


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