Table 2

Inferred amino acid replacements in COX2p and COX4p that occur in proximity to positively selected sites in COX5Ap among anthropoid primate stem lineages.

COX5Ap

COX2p

COX4p


Residue

Lineage

Residue

Lineage

Residue

Lineage


5 (H to Q)

Ape stem

52 (H to N)

Catarrhine* stem

(H to S)

New World monkey stem

54 (S to N)

Catarrhine stem

55 (T to I)

Catarrhine stem

56 (M to T)

Catarrhine stem

56 (T to S)

Large-bodied ape stem

57 (D to N)

New World monkey stem

38 (G to T)

Anthropoid stem

52 (H to N)

Catarrhine stem

54 (S to N)

Catarrhine stem

55 (T to I)

Catarrhine stem

22 (Y to H)

Ape stem

56 (M to T)

Catarrhine stem

56 (T to S)

Large-bodied ape stem

41 (L to M)

Ape stem

52 (H to N)

Catarrhine stem

54 (S to N)

Catarrhine stem

64 (A to T)

Anthropoid stem

63 (Q to K)

Catarrhine stem

70 (V to A)

Anthropoid stem

22 (Y to H)

Ape stem


Interaction is taken as a distance < 10 Å between residues.

*Catarrhines include Old World monkeys and apes, including humans

Uddin et al. BMC Evolutionary Biology 2008 8:8   doi:10.1186/1471-2148-8-8

Open Data