Complex signatures of selection for the melanogenic loci TYR, TYRP1 and DCT in humans

Santos Alonso¹ , Neskuts Izagirre¹ , Isabel Smith-Zubiaga² , Jesús Gardeazabal³ , José Luís Díaz-Ramón³ , José Luís Díaz-Pérez³ , Diana Zelenika⁴ , María Dolores Boyano⁵ , Nico Smit⁶ and Concepción de la Rúa¹

¹Dept. Genetics, Physical Anthropology and Animal Physiology. University of the Basque Country. Barrio Sarriena s/n. 48940 Leioa, Bizkaia, Spain

²Dept. Zoology and Animal Cell Biology. University of the Basque Country. Barrio Sarriena s/n. 48940 Leioa, Bizkaia, Spain

³Dermatology Service. Cruces Hospital. Plaza de Cruces s/n, 48903, Cruces-Barakaldo, Bizkaia, Spain

⁴Centre National de Génotypage (CNG). 2 Rue Gaston Cremieux. CP 5721. 91057 Evry Cedex, France

⁵Dept. Cell Biology and Histology. University of the Basque Country. Barrio Sarriena s/n. 48940 Leioa, Bizkaia, Spain

⁶Department of Clinical Chemistry, L01-036 Leiden University Medical Center, Albinusdreef 2, 2333 AZ Leiden, The Netherlands