Table 4

Parameters inferred for positive amino-acid mutations in D. miranda and D. melanogaster

D. miranda

D. melanogaster

K_a (%)^a

0.57

2.90

K_s (%)^a

4.21

14.91

π_s (%)^a

0.62

2.48

ρ/site/generation^b

8.8E-08

3.3E-08

μ/site/generation^c

5.8E-09

5.8E-09

α^d

0.44

0.51

T = (K_s-π_s)/(2μ)

3,093,681

10,716,289

θ₀ (%)^e

0.99

2.81

2N_es* α^e

1353.8

37.9

N_e = θ₀/(3μ)

568,851

1,613,218

2N_es

3103

74

s

2.7E-03

2.3E-05

λ = (α *K_a)/(2T)

4.0E-10

7.0E-10

2N_es* λ

1.2E-06

5.1E-08

u_ben = λ/(4*N_es)

6.5E-14

4.7E-12

^a estimated from polymorphism data

^b from True et al. (1996) and Oritz-Barrientos et al. (2006)

^c from Haag-Liautard et al. (2007)

^d estimated from polymorphism data using Bierne & Eyre-Walker (2004)

^e estimated from polymorphism data using Wiehe & Stephan (1993) model

Bachtrog BMC Evolutionary Biology 2008 8:334   doi:10.1186/1471-2148-8-334