BMC Evolutionary Biology

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Open Access

Evidence against the energetic cost hypothesis for the short introns in highly expressed genes

Yi-Fei Huang and Deng-Ke Niu*

BMC Evolutionary Biology 2008, 8:154 doi:10.1186/1471-2148-8-154

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Research   Open Access

Selection for the compactness of highly expressed genes in Gallus gallus

You S Rao, Zhang F Wang, Xue W Chai, Guo Z Wu, Ming Zhou, Qing H Nie, Xi Q Zhang Biology Direct 2010, 5:35 (14 May 2010)

Research   Open Access

In plants, expression breadth and expression level distinctly and non-linearly correlate with gene structure

Hangxing Yang Biology Direct 2009, 4:45 (21 November 2009)

Hypothesis   Open Access

Exon definition as a potential negative force against intron losses in evolution

Deng-Ke Niu Biology Direct 2008, 3:46 (13 November 2008)

If the splicing of pre-mRNAs is initiated by exon definition, an exon larger than a particular size may cause splicing errors . Intron loss that results in oversized exons may thus be deleterious and selected against.