The repertoire of G protein-coupled receptors in the sea squirt Ciona intestinalis

N Kamesh , Gopala K Aradhyam and Narayanan Manoj

Department of Biotechnology, Bhupat and Jyothi Mehta School of Biosciences Building, Indian Institute of Technology Madras, Chennai 600036, India

author email corresponding author email

BMC Evolutionary Biology 2008, 8:129doi:10.1186/1471-2148-8-129


Published:	1 May 2008

Additional files

Additional file 1:

Protein sequences of all Ciona GPCRs identified in this study in FASTA format

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Additional file 2:

Ciona GPCRs with homologs in Humans and other genomes (Sheet 1) and EST-HITS of Ciona GPCRs sorted by developmental stage/tissue (Sheet 2)

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Additional file 3:

Domain architecture of LDLRR-GPCR/LGR-like/GLHR receptor cluster in Ciona

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Additional file 4:

Multiple sequence alignment of human and rat PTHRs with homologs from Ciona. Alignment was generated in MAFFT using gap penalty of 1.53 and offset value 0.123. Scoring matrix is based on JTT200. Colored amino acids are used to refer functionally important residues known in human and rat PTHR1 and their putative homologs in Ciona and human PTHR2. Furthermore transmembrane regions are colored and sequence conservation and similarity represented symbolically.

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Additional file 5:

The GRAFSCM (Glutamate, Rhodopsin, Adhesion, Frizzled, Secretin, cAMP GPCR-like, Methuselah-like) phylogenetic tree in standard Newick format.

Format: TRE Size: 4KB Download file

Additional file 6:

The non-(LDLRR-GPCR/LGR) Rhodopsin phylogenetic tree in standard Newick format

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