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Resolution: standard / high Figure 3.
Fragments of alignments of simulated sequences. Simulations were done with (a) or without (b) among-site rate heterogeneity. Both
simulation were performed with Rose, following the tree represented in Figure 1 multiplied
by a factor of 1.5. Positions of the alignments where more than 50% of the sequences
are identical are shown with black boxes. The trees recalculated from the respective
complete alignments are also shown, with the scale in amino acid substitutions/site.
Interestingly, despite there being a very similar genetic distance between A and G
in both alignments, A finds G by Blast in the alignment evolved under rate heterogeneity
(A) but not in the alignment without rate heterogeneity (B).
AlbĂ and Castresana BMC Evolutionary Biology 2007 7:53 doi:10.1186/1471-2148-7-53 |