Figure 5.

Interaction of Asp-742 with other residues on the GR. The Asp-742 backbone oxygen and nitrogen form hydrogen bonds with backbone oxygen and nitrogen on nearby residues. Asp-742 also forms a hydrogen bond with Oγ1 on Thr-744. The side chain on Lys-743 is pointed away from the GR core and could interact with proteins that bind to the GR.