Functional and evolutionary analysis of alternatively spliced genes is consistent with an early eukaryotic origin of alternative splicing

doi:10.1186/1471-2148-7-188

BMC Evolutionary Biology
Volume 7

Viewing options:

Abstract
Full text
PDF (456KB)
Additional files

Associated material:

Related literature:

Articles citing this article
on BioMed Central
on Google Scholar
on ISI Web of Science
on PubMed Central
Other articles by authors
on Google Scholar

Irimia M
Rukov JL
Penny D
Roy SW

on PubMed

Irimia M
Rukov JL
Penny D
Roy SW
Related articles/pages
on Google

on Google Scholar

on PubMed

Tools:

Post to:

Research article

Functional and evolutionary analysis of alternatively spliced genes is consistent with an early eukaryotic origin of alternative splicing

Manuel Irimia¹^,2 , Jakob Lewin Rukov³ , David Penny¹ and Scott William Roy¹

¹Allan Wilson Centre for Molecular Evolution and Ecology, Massey University, Palmerston North, New Zealand

²Departament de Genètica, Universitat de Barcelona, Barcelona, Spain

³Department of Molecular Biology, University of Copenhagen, Copenhagen, Denmark

author email corresponding author email

BMC Evolutionary Biology 2007, 7:188doi:10.1186/1471-2148-7-188


Published:	4 October 2007

Additional files

Additional file 1:

Ancient alternatively spliced KOG's. List of 36 ancient KOG (appeared before the split of animals, fungi and plants) that show high AS incidence in A. thaliana, D. melanogaster, C. elegans and H. sapiens.

Format: XLS Size: 22KB Download file

This file can be viewed with: Microsoft Excel Viewer

Additional file 2:

Cellular locations and alternative splicing. List of different cellular locations and their AS frequency for A. thaliana, D. melanogaster, C. elegans, C. neoformans, M. musculus and H. sapiens.

Format: XLS Size: 56KB Download file

This file can be viewed with: Microsoft Excel Viewer

Additional file 3:

Molecular functions and alternative splicing. List of different molecular functions and their AS frequency for A. thaliana, D. melanogaster, C. elegans, C. neoformans, M. musculus and H. sapiens.

Format: XLS Size: 118KB Download file

This file can be viewed with: Microsoft Excel Viewer

Additional file 4:

Biological Processes and alternative splicing. List of different biological processes and their AS frequency for A. thaliana, D. melanogaster, C. elegans, C. neoformans, M. musculus and H. sapiens.

Format: XLS Size: 125KB Download file

This file can be viewed with: Microsoft Excel Viewer

Additional file 5:

EST/cDNAs Sampling Bias Control. Control for EST/cDNAs sampling bias. It has been performed in C. elegans. The document contains 4 figures, corresponding to: cellular locations (C), molecular functions (F), biological process (P) and species groups.

Format: PDF Size: 173KB Download file

This file can be viewed with: Adobe Acrobat Reader