Table 4 |
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M. leprae PE, PGRS and PPE genes |
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PE genes |
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M. leprae gene number |
M. leprae gene name* |
M. tuberculosis orthologue gene number |
M. tuberculosis orthologue gene name |
|
|
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|
ML0196c (pseudogene) |
PE 1 |
Rv3650 |
PE33 |
|
ML0263c (pseudogene) |
PE2 |
Rv1040c |
PE8 |
|
ML0410 |
PE3 |
M. leprae-specific |
- |
|
ML0538 |
PE4 |
Rv1386 |
PE15 |
|
ML1053 |
PE5 |
Rv1195 |
PE13 |
|
ML1183c |
PE6 |
M. leprae-specific paralogue of Rv1195 |
- |
|
ML1493 (pseudogene) |
PE7 |
Rv1172c |
PE12 |
|
ML1534c (pseudogene) |
PE8 |
Rv1806 |
PE20 |
|
ML1743c (pseudogene) |
PE9 |
M. leprae-specific |
- |
|
ML2534c |
PE10 |
Rv0285 |
PE5 |
|
ML2632 (pseudogene) |
PE11 |
Rv0160c |
PE4 |
|
ML1865c (pseudogene) |
- |
M. leprae-specific |
- |
|
ML2129c (pseudogene) |
- |
M. leprae-specific |
- |
|
ML 2477 (pseudogene) |
- |
Rv3746c |
PE34 |
|
|
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PE_PGRS genes |
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|
M. leprae gene number |
M. leprae gene name* |
M. tuberculosis orthologue gene number |
M. tuberculosis orthologue gene name |
|
|
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|
ML0194c (pseudogene) |
PE_PGRS1 |
Rv3653 |
PE_PGRS61 |
|
ML0495 (pseudogene) |
PE_PGRS2 |
M. leprae-specific |
- |
|
ML1092c (pseudogene) |
PE_PGRS3 |
Rv1243c |
PE_PGRS23 |
|
ML1403 (pseudogene) |
PE_PGRS4 |
Rv1651c |
PE_PGRS30 |
|
ML1414 (pseudogene) |
PE_PGRS5 |
M. leprae-specific |
- |
|
ML2241c (pseudogene) |
PE_PGRS6 |
Rv0754 |
PE_PGRS11 |
|
ML0147 (pseudogene) |
- |
M. leprae-specific |
- |
|
ML0946 |
- |
M. leprae-specific |
- |
|
|
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PPE genes |
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M. leprae gene number |
M. leprae gene name* |
M. tuberculosis orthologue gene number |
M. tuberculosis orthologue gene name |
|
|
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|
ML0026 (pseudogene) |
PPE1 |
M. leprae-specific |
- |
|
ML0277 (pseudogene) |
PPE2 |
Rv0388c |
PPE9 |
|
ML0328c (pseudogene) |
PPE3 |
M. leprae-specific paralogue of Rv3021c |
paralogue of PPE47 |
|
ML0503 (pseudogene) |
PPE4 |
M. leprae-specific |
- |
|
ML0539 |
PPE5 |
Rv1387 |
PPE20 |
|
ML0797c (pseudogene) |
PPE6 |
M. leprae-specific |
- |
|
ML0828 (pseudogene) |
PPE7 |
Rv2352c |
PPE38 |
|
ML1054 (pseudogene) |
PPE8 |
Rv1196 |
PPE18 |
|
ML1182c |
PPE9 |
M. leprae-specific paralogue of Rv1196 |
- |
|
ML1308c (pseudogene) |
PPE10 |
Rv2123 |
PPE37 |
|
ML1533c (pseudogene) |
PPE11 |
Rv1807 |
PPE31 |
|
ML1828c |
PPE12 |
Rv0256c |
PPE2 |
|
ML1991 |
PPE13 |
Rv0096 |
PPE1 |
|
ML2369c (pseudogene) |
PPE14 |
Rv0442c |
PPE10 |
|
ML2533c (pseudogene) |
PPE15 |
Rv0286 |
PPE4 |
|
ML2538c (pseudogene) |
PPE16 |
M. leprae-specific, situated between Rv0281 and 82 |
- |
|
ML0051c |
PPE68 |
Rv3873 |
PPE68 |
|
ML0411 |
- |
M. leprae-specific |
- |
|
not annotated, situated between ML0262c and 63c (pseudogene) |
- |
Rv1039c |
PPE15 |
|
ML1754 (pseudogene) |
- |
Rv1361c |
PPE19 |
|
ML0588 |
- |
M. leprae-specific |
- |
|
ML1935c (pseudogene) |
- |
M. leprae-specific |
- |
|
ML1967c (pseudogene) |
- |
M. leprae-specific |
- |
|
ML1968c (pseudogene) |
- |
M. leprae-specific |
- |
|
ML2128c (pseudogene) |
- |
M. leprae-specific |
- |
|
ML2243c (pseudogene) |
- |
M. leprae-specific |
- |
|
|
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* Regrettably, and in contrast to the annotation of the PE and PPE genes in M. bovis, the genes in M. leprae are annotated according to their own PE and PPE numbers and not according to the same numbers as its corresponding orthologue in M. tuberculosis, with the only exception being PPE68 which have the same name in both species. |
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Gey van Pittius et al. BMC Evolutionary Biology 2006 6:95 doi:10.1186/1471-2148-6-95 |
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