Figure 4.

Phylogeny of the PE and PPE protein families present within the ESAT-6 (esx) gene clusters in M. tuberculosis H37Rv. Phylogenetic trees of the PE and PPE proteins, respectively, present within the ESAT-6 (esx) gene clusters in M. tuberculosis H37Rv, demonstrating a duplication order similar to that observed with other genes in the M. tuberculosis ESAT-6 (esx) gene cluster regions [1]. (A) PE proteins, (B) PPE proteins and (C) ESAT-6/CFP-10 proteins.