|
The twelve families of universally conserved genes missing in mammals |
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| Gene Family Name1 |
A.t2 |
S.c2 |
A.g2 |
D.m2 |
C.e2 |
Loss extends to |
Function |
EC |
KEGG pathway |
|
|
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| ACH |
0 |
1 |
1 |
1 |
1 |
Deutero. |
Acetyl-CoA Hydrolase, Pyruvate Metabolism |
3.1.2.1 |
sce00620 |
| TPS |
4 |
1 |
1 |
1 |
2 |
Deutero. |
Trehalose 6P biosynthesis |
2.4.1.15 |
Sce00500 |
| YD56 |
4 |
3 |
2 |
1 |
1 |
Chordates |
Multicopper Ion transporter |
1.-.-.- |
XXX |
| YMT1 |
1 |
1 |
1 |
3 |
1 |
Chordates |
Putative oxidroeductase and K+ ion transporter |
XXX |
XXX |
| PNC1 |
0 |
1 |
1 |
1 |
1 |
Chordates |
Nicotinate and Nicotinamide Metabolism |
3.5.1.19 |
sce00760 |
| YM74 |
3 |
2 |
1 |
1 |
1 |
Chordates |
Transcription factor activity/DNA Binding |
XXX |
XXX |
| THDH1/ILV1 |
1 |
1 |
1 |
1 |
2 |
Chordates |
Leucine, Isoleucine, Valine Biosynthesis. Threonine Metabolism |
4.3.1.19 |
sce00260 |
| GLT |
1 |
1 |
1 |
1 |
1 |
Chordates |
Glutamate synthesis |
1.4.1.13 |
sce00251 sce00910 |
| AMT/MEP -1,2,3 |
6 |
3 |
1 |
1 |
4 |
Eu-chordates |
Amonium Transporter |
XXX |
XXX |
| YKH1 |
0 |
1 |
1 |
1 |
9 |
Mammals |
Metabolism, oxidoreductase |
XXX |
XXX |
| URH1 |
2 |
1 |
3 |
3 |
2 |
Mammals |
Uridine catabolism, hydrolase activity |
3.2.2.3 |
XXX |
|
1 Gene family name is given according to the gene's name in Saccharomyces cerevisiae. 2 Number of gene copies from the considered family present in the genome, for each model species, A.t = Arabidopsis thaliana, S.c = Saccharomyces cerevisiae, A.g = Anopheles gambiae, D.m = Drosophila melanogaster, C.e = Caenorhabditis elegans. 3 KEGG's biochemical pathway's accession number for Saccharomyces cerevisiae. | |||||||||
Danchin et al. BMC Evolutionary Biology 2006 6:5 doi:10.1186/1471-2148-6-5 |
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