Tracking the evolution of alternatively spliced exons within the Dscam family

doi:10.1186/1471-2148-6-16

BMC Evolutionary Biology
Volume 6

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Research article

Tracking the evolution of alternatively spliced exons within the Dscam family

Mack E Crayton III^*¹^,5 , Bradford C Powell^*³ , Todd J Vision⁴ and Morgan C Giddings¹^,2

¹Department of Microbiology and Immunology, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA

²Department of Biomedical Engineering, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA

³Curriculum in Genetics and Molecular Biology, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA

⁴Department of Biology, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA

⁵Department of Biology, Xavier University of Louisiana, New Orleans, LA 70125, USA

author email corresponding author email* Contributed equally

BMC Evolutionary Biology 2006, 6:16doi:10.1186/1471-2148-6-16


Published:	16 February 2006

Additional files

Additional File 1:

Alignment of Dscam exon 4 homologs. Alignment of sequences found using variants of Dscam exon 4 from Drosophila as queries. ClustalW format, viewable as plain text.

Format: TXT Size: 10KB Download file

Additional File 2:

Alignment of Dscam exon homologs. Alignment of sequences found using variants of Dscam exon 6 from Drosophila as queries. ClustalW format, viewable as plain text.

Format: TXT Size: 9KB Download file

Additional File 3:

Alignment of Dscam exon 9 homologs. Alignment of sequences found using variants of Dscam exon 9 from Drosophila as queries. ClustalW format, viewable as plain text.

Format: TXT Size: 15KB Download file

Additional File 4:

Alignment of Dscam exon 17 homologs. Alignment of sequences found using variants of Dscam exon 17 from Drosophila as queries. ClustalW format, viewable as plain text.

Format: TXT Size: 2KB Download file

Additional File 5:

Locations of sequences similar to Dscam exons. Locations of the sequences referenced in additional files 1, 2, 3, 4 and in the text. Locations are given on chromosomal assemblies from Ensembl version 20 or from contigs referenced in the methods. The file is in Microsoft Excel format. Stop coordinates less than start coordinates indicate that elements are in the (-) strand.

Format: XLS Size: 54KB Download file

This file can be viewed with: Microsoft Excel Viewer

Additional File 6:

A Smith-Waterman alignment of fly Dscam versus Human Dscam, with the sequences corresponding to exons highlighted by color (color legend in the file), and putative corresponding domain locations underlined.

Format: PDF Size: 42KB Download file

This file can be viewed with: Adobe Acrobat Reader

Additional File 7:

A Smith-Waterman alignment of fly Dscam versus Human Dscam-L, with the sequences corresponding to exons highlighted by color (color legend in the file), and putative corresponding domain locations underlined.

Format: PDF Size: 41KB Download file

This file can be viewed with: Adobe Acrobat Reader