Additional file 1.
Prediction of transmembrane domains (TMs) in human GnRHR1 and Ce-GnRHR. The sequence alignment of human GnRHR1 and Ce-GnRHR presented here is taken from Figure 1; Thus for consistency, some sites are represented by gaps in both sequences. Functionally important residues (FIRs) are colored (see legend for classification). Overall, there is 56 % similarity between the FIRs of human GnRHR1 and Ce-GnRHR. TMs for both human GnRHR1 and the Ce-GnRHR were predicted using multiple programs described in Methods and are represented as colored lines above/below the alignment. Each program predicted Ce-GnRHR, like human GnRHR1, to have 7 TMs.
Format: EPS Size: 2.1MB Download file
Vadakkadath Meethal et al. BMC Evolutionary Biology 2006 6:103 doi:10.1186/1471-2148-6-103