Table 3

Paralogous gene families expanded in DR

Description

COG numbers

Number of representatives in DR

Number of representatives in TT


Widespread families expanded in DR

MutT-like phosphohydrolases (Nudix)

COG0494, COG1051

17,5

5,5

Calcineurin-like phosphoesterase

COG1768, COG1408, COG1692, COG0639

1; 1; 1; 9

1; 0; 1; 2

Lipase-like alpha/beta hydrolase

COG0596, COG0400

10; 1

6; 1

Subtilisin-like protease

COG1404

10

2

Sugar deacetylase

COG2120

6

4

PadR-like transcriptional regulators (possibly involved in chemical stress response)

COG1695

9

0

MOSC sulfur-carrier domains

COG2258

4

1

FlaR like kinases

-

3

0

LigT phosphatases (may participate in RNA repair or methabolism)

-

3

2

McrA endonuclease

COG1403

5

1

TerZ family (could confer resistance to a variety of DNA-damaging agents)

COG2310

7

0

PR1 family (stress response)

COG2340

5

1

DinB family (DNA damage and stress inducible proteins)

COG2318; no COG

3; 10

1

Transcriptional regulators

-

5

0

Unique DR families

GRXGG repeats containing protein

-

DR0082, DR2593, DR1748

No

Alpha/beta proteins, tryptophan-rich

-

DR2532, DR2457

No

Proteins with GXTXXXG and CXPXXXC motifs (DR0871 has duplication of the domain)

-

DR0871, DR1920, DR2360

No

Secreted alpha/beta proteins with a single conserved domain

-

DR1251, DR1319, DR1545

No

Predominantly alpha-helical proteins

-

DR0481, DR1195, DR1301

No

Predominantly alpha-helical proteins

-

DR0387, DR2038+DR2039

No

Predicted metabolic regulator containing V4R domain

-

DR2179, DR1611

No

Predicted sirohydrochlorin cobaltochelatase

COG2138

DRA0012, DR2241

No

Conserved histidine rich protein (now also found in Caulobacter and Mesorhizobium)

COG3798

DR1261, DR1348

No


Omelchenko et al. BMC Evolutionary Biology 2005 5:57   doi:10.1186/1471-2148-5-57

Open Data