Comparative genomics of Thermus thermophilus and Deinococcus radiodurans: divergent routes of adaptation to thermophily and radiation resistance

doi:10.1186/1471-2148-5-57

BMC Evolutionary Biology

Volume 5

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Omelchenko MV
Wolf YI
Gaidamakova EK
Matrosova VY
Vasilenko A
Zhai M
Daly MJ
Koonin EV
Makarova KS

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Omelchenko MV
Wolf YI
Gaidamakova EK
Matrosova VY
Vasilenko A
Zhai M
Daly MJ
Koonin EV
Makarova KS
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Research article

Comparative genomics of Thermus thermophilus and Deinococcus radiodurans: divergent routes of adaptation to thermophily and radiation resistance

Marina V Omelchenko¹^,2 , Yuri I Wolf² , Elena K Gaidamakova¹ , Vera Y Matrosova¹ , Alexander Vasilenko¹ , Min Zhai¹ , Michael J Daly¹ , Eugene V Koonin² and Kira S Makarova²

¹Department of Pathology, F.E. Hebert School of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD 20814-4799, USA

²National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD 20894, USA

author email corresponding author email

BMC Evolutionary Biology 2005, 5:57doi:10.1186/1471-2148-5-57


Published:	20 October 2005

Additional files

Additional File 1:

(contains supplementary text and supplementary tables 1S, 2S, 3S, 4S and supplementary figures 1S, 2S, 3S)

Format: DOC Size: 659KB Download file

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Additional File 2:

contains the assignments of DR and TT proteins to the COG database.

Format: XLS Size: 1.3MB Download file

This file can be viewed with: Microsoft Excel Viewer

Additional File 6:

contains compressed file for all the trees (in PHYLIP format) for 122 proteins from the reconstructed gene set of the DR-TT common ancestor that showed affinity to thermophiles (see also 1: "Phylogenetic analysis of the genes of the reconstructed DR-TT common ancestor").

Format: ZIP Size: 46KB Download file

Additional File 3:

contains DR and TT protein comparison with COGs predicted to be associated with the thermophilic phenotype.

Format: XLS Size: 43KB Download file

This file can be viewed with: Microsoft Excel Viewer

Additional File 4:

contains the results of the reconstruction of the gene repertoire of the common ancestor of TT and DR.

Format: XLS Size: 393KB Download file

This file can be viewed with: Microsoft Excel Viewer

Additional File 5:

contains information on taxonomic assignments for the best hits of the TT and DR proteins.

Format: XLS Size: 982KB Download file

This file can be viewed with: Microsoft Excel Viewer

Additional File 7:

contains compressed file for all the trees (in PHYLIP format) for proteins from DR-TT core that had best hits to thermophiles.

Format: ZIP Size: 55KB Download file