BMC Evolutionary Biology

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Do orthologous gene phylogenies really support tree-thinking?

E Bapteste*, E Susko, J Leigh, D MacLeod, RL Charlebois and WF Doolittle

BMC Evolutionary Biology 2005, 5:33 doi:10.1186/1471-2148-5-33

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The fundamental units, processes and patterns of evolution, and the Tree of Life conundrum

Eugene V Koonin, Yuri I Wolf Biology Direct 2009, 4:33 (29 September 2009)

This article is part of a collection on Evolutionary Biology 150...

A tree is a natural representation of evolution owing to the inherent tree-like character of the replication process but the fundamental units of evolution amenable to tree analysis seem to be individual genetic elements rather than complete genomes.

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Search for a 'Tree of Life' in the thicket of the phylogenetic forest

Pere Puigbò, Yuri I Wolf, Eugene V Koonin Journal of Biology 2009, 8:59 (13 July 2009)

Koonin and colleagues, comparing a forest of 7000 phylogenetic trees, discern vertical inheritance even at the earliest stages of prokaryotic evolution, despite horizontal gene transfer, but the branching order of the earliest radiations may never be resolved.

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Co-evolutionary networks of genes and cellular processes across fungal species

Tamir Tuller, Martin Kupiec, Eytan Ruppin Genome Biology 2009, 10:R48 (5 May 2009)

Two new measures of evolution are used to study co-evolutionary networks of fungal genes and cellular processes; links between co-evolution and co-functionality are revealed.

Research article   Open Access

Factors affecting the concordance between orthologous gene trees and species tree in bacteria

Santiago Castillo-Ramírez, Víctor González BMC Evolutionary Biology 2008, 8:300 (30 October 2008)

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Evolutionary rate and gene expression across different brain regions

Tamir Tuller, Martin Kupiec, Eytan Ruppin Genome Biology 2008, 9:R142 (23 September 2008)

Cortically expressed genes are more conserved than sub-cortical ones and gene expression levels exert stronger constraints on sequence evolution in cortical than in sub-cortical regions.

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Uncovering rate variation of lateral gene transfer during bacterial genome evolution

Weilong Hao, G Brian Golding BMC Genomics 2008, 9:235 (20 May 2008)

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DarkHorse: a method for genome-wide prediction of horizontal gene transfer

Sheila Podell, Terry Gaasterland Genome Biology 2007, 8:R16 (2 February 2007)

DarkHorse is a new approach to rapid, genome-wide identification and ranking of horizontal transfer candidate proteins.

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Refuting phylogenetic relationships

James Bucknam, Yan Boucher, Eric Bapteste Biology Direct 2006, 1:26 (6 September 2006)

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A putative RNA-interference-based immune system in prokaryotes: computational analysis of the predicted enzymatic machinery, functional analogies with eukaryotic RNAi, and hypothetical mechanisms of action

Kira S Makarova, Nick V Grishin, Svetlana A Shabalina, Yuri I Wolf, Eugene V Koonin Biology Direct 2006, 1:7 (16 March 2006)

Computational analysis shows that CRISPR repeats and associated Cas proteins in prokaryotes might act in conjunction as a RNA-silencing mechanism against plasmids and viruses, similar to the eukaryotic RNA-interference system.

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Taxonomic colouring of phylogenetic trees of protein sequences

Gareth Palidwor, Emmanuel G Reynaud, Miguel A Andrade-Navarro BMC Bioinformatics 2006, 7:79 (17 February 2006)

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The largest subunit of RNA polymerase II from the Glaucocystophyta: functional constraint and short-branch exclusion in deep eukaryotic phylogeny

John W Stiller, Leslie Harrell BMC Evolutionary Biology 2005, 5:71 (9 December 2005)