Table 2

GenBank accession numbers for relaxin-like sequences. Accession numbers for all sequences included in the phylogeny are listed. New sequences identified in this study are highlighted in bold and accession numbers shown in brackets underneath. Phylogenetic analyses showed TrRLX3f, DrRLX3c, XtRLX3a and XlRLX3 sequences (shown in italics) to be relaxin rather than relaxin-3 homologs and are therefore listed in the relaxin (RLX2) column.

Species
RLX1
RLX2
RLX3
INSL3
INSL4
INSL5
INSL6

Human
P04808
P04090
Q8WXF3
P51460
Q14641
Q9Y5Q6
Q9Y581
Chimpanzee
S42783
P51455
BK005156b
BK005155b
BK005152b
BK005153b
BK005154b
Mouse
-
CAA81611
Q8CHK2
O09107
-
Q9WUG6
Q9QY05
Rat
-
J00780
Q8BFS3
AAD33663
-
-
Q9WV41
Dog
-
Q9TRM8
AAEX01023146
AAEX01022997


AAEX01053723
Wallaby

AAM22209





R. esculenta

CAC16108





Fugufish

RLX3f
BK005388b
RLX3a-c


RLX3d,e

Zebrafish

RLX3c
BK005255b
RLX3a
BK005228


RLX3b
BK005252a,b
RLX3d (b,c)

Chicken


RLX3a
BK005146a


RLX3b
BK005533b

Pig

P01348
Q8HY17
P51461



X. tropicalis

RLX3a
BK005229a
RLX3b(b,d)
RLX3c(b,d)




X. laevis

RLX3
BK005230a





O. mykiss





RLX3
BK005147a

M. mulatta




INSL4
BK005251a



aSequences determined from multiple overlapping ESTs.

bSequences determined from genomic data.

cSequence from the Ensembl zebrafish genome assembly [68](GENSCAN00000013529 on supercontig NA8544).

dSequence from the Xenopus genome v2.0 [58].

Wilkinson et al. BMC Evolutionary Biology 2005 5:14   doi:10.1186/1471-2148-5-14