Evolution of the relaxin-like peptide family

doi:10.1186/1471-2148-5-14

BMC Evolutionary Biology

Volume 5

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Research article

Evolution of the relaxin-like peptide family

Tracey N Wilkinson¹ , Terence P Speed² , Geoffrey W Tregear¹ and Ross AD Bathgate¹

¹Howard Florey Institute of Experimental Physiology and Medicine, University of Melbourne, Australia

²Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia

author email corresponding author email

BMC Evolutionary Biology 2005, 5:14doi:10.1186/1471-2148-5-14


Published:	12 February 2005

Additional files

Additional File 1:

Phylogeny of cluster A- relaxin-3 and INSL5. Phylogeny of Cluster A constructed from a ClustalW alignment of the B and A domain amino acid sequences from relaxin 3 and INSL5 peptides. Consensus tree generated from MP (Protpars in PHYLIP), ML (TreePuzzle) and NJ (Neighbour in PHYLIP) methods and edited in Treeview to minimize species tree incongruence. Human insulin was used as an outgroup. Where possible, confidence values are shown at branches: * >50%, ** >75%, all other branches are inferred. Hsa = Homo sapiens, Pt = Pan troglodytes, Mm = Mus musculus, Rn = Rattus norvegicus, Cf = Canis familiaris, Ss = Sus scrofa, Xt = Xenopus tropicalis, Dr = Danio rerio, Tr = Takifugu rubripes, Gg = Gallus gallus, Om = Oncorhynchus mykiss.

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Additional File 2:

Phylogeny of cluster B- relaxin-1, 2, INSL3, INSL4 and INSL6. Consensus phylogeny of Cluster B constructed from a ClustalW alignment of the B and A domain amino acid sequences from relaxin 1, 2, INSL3, INSL4, INSL6 peptides. Consensus tree generated from MP (Protpars in PHYLIP), ML (TreePuzzle) and NJ (Neighbour in PHYLIP) methods and edited in Treeview to minimize species tree incongruence. Human insulin was used as an outgroup. Where possible, confidence values are shown at branches: * >50%, ** >75%, all other branches are inferred. Hsa = Homo sapiens, Pt = Pan troglodytes, Mmul = Maca mulatta, Mm = Mus musculus, Rn = Rattus norvegicus, Cf = Canis familiaris, Ss = Sus scrofa, Re = Rana esculenta, Me = Macropus eugenii, Xl = Xenopus laevis, Xt = Xenopus tropicalis, Dr = Danio rerio, Tr = Takifugu rubripes.

Format: DOC Size: 26KB Download file

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