Figure 1.

Effect of mutations and their combinations on acetylthiocholine hydrolysis versus substrate concentration (log scale). The frequency of each allele found by sequencing ace of 29 Drosophila populations from many parts of the world is provided for each mutant. (blue circle): wild type; (red circle): mutant. [ATCh]: Acetylthiocholine concentration in micromole per liter ; v/ [Et] specific activity in s^-1.