Table 3 |
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|
Synonymous vs. non-synonymous codon substitution between C. elegans and C. briggsae AADC orthologs and bas-1-like paralogs. |
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|
Ce, Cb AADCs compared |
Codons |
pS |
pN |
KA/KS |
|
|
||||
|
bas-1 |
521 |
0.68 |
0.07 |
0.039 |
|
C05D2.3, F12A10.3, bas-1* |
521 |
0.71 ± 0.03 |
0.26 ± 0.02 |
0.148 ± 0.044 |
|
ZK289.2 |
833 |
0.71 |
0.09 |
0.043 |
|
C09G9.4 |
507 |
0.74 |
0.12 |
0.037 |
|
tdc-1 full length |
626 |
0.79 |
0.03 |
NA |
|
tdc-1 core |
474 |
0.82 |
0.02 |
NA |
|
tdc-1 N, C terminals |
152 |
0.71 |
0.07 |
0.035 |
|
|
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|
Nucleotide alignments of C. elegans and C. briggsae genes were analyzed by SNAP software (see Methods). Only the C. elegans member of the ortholog pair is named. pS = proportion of observed/potential synonymous substitutions; pN = proportion of observed/potential nonsynonymous substitutions. NA – not applicable (cannot be calculated when pS > 0.75). *Includes all pairwise comparisons (n = 5) except C.e. vs. C.b. bas-1. Values are mean ± SD (strict statistical comparison with other values is not intended, as KA/KS values are not distributed normally). |
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|
Hare and Loer BMC Evolutionary Biology 2004 4:24 doi:10.1186/1471-2148-4-24 |
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