Table 3

Correlation between ortholog substitution levels and the substitution levels between the most closely related paralogs

Speciesa

Slopeb

r2c

Pd


Human – Mouse

6.1 × 10-2

3.3 × 10-2

3.3 × 10-87

Drosophila Anopheles

6.5 × 10-2

2.3 × 10-2

7.6 × 10-27

S. cerevisiae C. albicans

2.1 × 10-1

1.0 × 10-1

1.1 × 10-38

E. coli Y. pestis

3.3 × 10-2

3.0 × 10-3

9.0 × 10-2

B. subtilis B. halodurans

1.6 × 10-1

4.2 × 10-2

3.1 × 10-11

P. horikoshii P. furiosis

6.3 × 10-2

1.7 × 10-2

1.0 × 10-3


a Species for which comparisons were performed b Slope of the linear regression line (i.e. y from the equation y = mx + b) c Square of the correlation coefficient (corresponds to the fraction of variation in ortholog evolutionary rates explained by the variation in paralog evolutionary rate) d P-value for correlation coefficient

Jordan et al. BMC Evolutionary Biology 2004 4:22   doi:10.1186/1471-2148-4-22

Open Data