Gene order and orientation in regions surrounding NAT genes on chicken (Gallus gallus) chromosome 11, turkey (Meleagris gallopavo) chromosome 13 and zebra finch (Taeniopygia guttata) chromosomes 11 and Un. Gene lengths and intergenic distances are not drawn to scale. Grey boxes indicate NAT-like sequences. Black boxes represent chicken-specific genes with no homologous sequences in turkey or zebra finch. Double slashes (//) indicate continuing sequence data extending toward the centromeric (cen) and telomeric (tel) parts of the chromosome. In each species, NAT genes are arrayed linearly along a single chromosome, indicating an expansion of the NAT gene family through tandem repeats, except in zebra finch where a fifth copy is found on an unidentified (Un) chromosome. Chicken NAT4 (chr11:17,483,758-17,484,630 in galGal3 assembly) represents a short sequence of 873 bp, identical to the NAT3 protein-coding sequence, which is embedded within the NAT3 gene (chr11:17,481,972-17,493,917) upstream of the NAT3 coding sequence.
Sabbagh et al. BMC Evolutionary Biology 2013 13:62 doi:10.1186/1471-2148-13-62