Table 2

Nuclear export and localization signals in Sirtuin family
PROTEIN SIRT1 SIRT2 SIRT3 SIRT4 SIRT5 SIRT6 SIRT7
N-terminal NES NES NES NES NES NES NES
NLS
C-terminal NES ( ciona ) NES ( ciona )

NES or NLS indicates the presence of the signal in a specific group of Sirtuins. No NLS signal has been found in the C-terminal segments.

Costantini et al.

Costantini et al. BMC Evolutionary Biology 2013 13:60   doi:10.1186/1471-2148-13-60

Open Data