Effect of OtaL on the affinity of OtaS for 3-PGA. The OtaS homotetramer is similarly activated by 3-PGA and FBP, whereas the mutant OtaS/OtaLD171A heterotetramer has a higher affinity for 3-PGA than FBP. The plots show the activation of OtaS (A) and OtaS/OtaLD171A (B) by 3-PGA (▪) and FBP (·).
Kuhn et al. BMC Evolutionary Biology 2013 13:51 doi:10.1186/1471-2148-13-51