Additional file 2.
Multiple sequence alignments of the newly obtained seven cetacean Hr deduced amino acids. The positions of the three repression domains (RD1, RD2, RD3), nuclear localization signal (NLS), zinc-finger domain and JmjC domain are indicated [7,31]. Interacting domains 1 and 2 (ID1 and ID2) mediating the interaction between Hr and the retinoic acid receptor-related orphan receptor-alpha (RORα)  or with the thyroid hormone receptor (TR)  are boxed. Cysteine residues involved in formation of the potential zinc finger are highlighted in blue. Deletions and mutations of the five toothed whales are highlighted in yellow and red, respectively.
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Chen et al. BMC Evolutionary Biology 2013 13:34 doi:10.1186/1471-2148-13-34