Table 2

Examples of inactivating mutations in enamel matrix protein genes among edentulous and enamelless amniotes with genome sequences
Taxon Inactivating mutations
ENAM AMBN AMEL
Cryptodira None None Possible shared frameshift mutations in exon 2 (see AF9)
Chrysemys AF1 Insertions: 65, 271, 411, 485, 994-1138 (Cry), 2526-2529, 2559-2571, 3268 AF3 Insertions: 956-957, 972, 1051-1052 AF7 Deletion: 106
AF1 Deletions: 588, 1264-1276, 3325-3343 AF3 Deletions: 497-498, 605-611, 794-804, 984-985
Pelodiscus Gene not recovered Gene not recovered AF7 Deletions: 122-125, 208, 271, 276
Neognathae AF1 Insertions: 1985-1989, 2143-2144, AF3 Deletion: 515-524 AF7 Deletions: 134 (with subsequent deletion of one additional bp in Taeniopygia), 242, 709-710
AF1 Deletions: 2634-2637, 3353-3758
Galloanserae AF1 Deletion: 1189-1192 None AF7 Deletions: 173-174, 282-289
Anas AF1 Insertions: 552-562, 2031-2040 AF3 Deletions: 216-217, 226, 455, 727-728 AF7 Insertions: 152, 181
AF1 Deletions: 2626-2627 AF7 Deletion: 88-94
Gallus + Meleagris AF1 Insertion: 2654 None AF7 Insertion: 484
AF1 Deletion: 3263-3267
Gallus AF1 Insertions: 512, 930-931 AF3 Insertions: 225, 230 AF7 Deletion: 275-276
AF1 Deletions: 126-127, 585-595
Meleagris AF1 Insertion: 2438-2441 Gene not recovered AF7 Deletion: 359
Taeniopygia + Melopsittacus AF1 Deletion: 2958 None None
Taeniopygia AF1 Deletion: 3318 AF3 Deletions: 578, 612-613 AF7 Deletions: 378, 407-417
Melopsittacus AF1 Insertions: 231, 2239 AF3 Stop codon: 708-710 AF7 Insertion: 105
AF1 Deletions: 432-433, 452-453, 504-505 AF7 Deletions: 91–94, 387
Dasypus See Meredith et al. [2] None AF11 Deletion: 3’ end of intron 6, including the acceptor splice site, and the first 14 bp of exon 7 (665–678), which includes the last amino acid and the stop codon
Choloepus See Meredith et al. [2] Splice site mutation: AG to AT at intron 2 acceptor site (gb|ti|1338556193) AF11 Deletions: 45–55, 600
AF11 Initiation codon mutation: ATG to ACG (13–15)
AF11 Stop codon: 356-358
Orycteropus See Meredith et al. [2] AF5 Deletions: 415-651 (all of exon 6), 1241-1253 AF11 Stop codons: 239–241, 299-301
AF5 Stop codon: 388-390

Numbers correspond to sequence alignment positions in Additional files. Additional file 1 = AF1; Additional file 3 = AF3; Additional file 5 = AF5; Additional file 7 = AF7; Additional file 9 = AF9; Additional file 11 = AF11. Cry = Cry SINE [47].

Meredith et al.

Meredith et al. BMC Evolutionary Biology 2013 13:20   doi:10.1186/1471-2148-13-20

Open Data