Additional file 11.

Nexus alignment of AMEL sequences (exons 2–7) for Homo sapiens, Orycteropus afer and six other afrotherians (Echinops telfairi, Chrysochloris asiatica, Elephantulus edwardii, Trichechus manatus, Loxodonta africana, Procavia capensis), Dasypus novemcinctus, and Choloepus hoffmanni. The start and stop codons in Homo occur at positions 13–15 (exon 2) and 668–670 (exon 7), respectively. The mutated stop codon and frameshift mutation in exon 2 of Choloepus are clear in gnl|ti|1325289135 and gnl|ti|1311883086. The stop codon in exon 4 of Choloepus is confirmed by traces gnl|ti|1325336699 and gnl|ti|1312095734. The frameshift mutation in exon 6 of Choloepus is evident in trace gnl|ti|1363579107. The deletion that includes the 3’ region of intron 6 and first 14 bp of exon 7 in Dasypus is evident in gn|ti| 1886397515.

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Meredith et al. BMC Evolutionary Biology 2013 13:20   doi:10.1186/1471-2148-13-20