Coevolution leads to diversification of bacteria and phage. Plots show time series (A-C), adaptive landscapes with superimposed genotype density distributions (D-G), growth rate function (H), and growth-lysis correlations (I). A: Resource concentration R, supply R0, and R∗ for optimal growth phenotype. B: Total bacteria/phage density. C: Density distribution of bacteria and phage genotypes. D: Rate of change of bacterial genotype density (). E: Bacterial genotype growth rate (). F: Bacterial genotype lysis rate (). G: Rate of change of phage genotype density (). H: Growth rate for bacterial genotypes. I: Correlation between growth and lysis rates for all bacterial strains forming >1%of total cell density, measured in three time intervals. All correlations (r) are significant with p<10−19in all cases. Parameter settings as Table 1.
Williams BMC Evolutionary Biology 2013 13:17 doi:10.1186/1471-2148-13-17