Haplotype genealogies constructed with HapView. The circle size is proportional to the haplotype frequency. Each line represents a single mutation; dark blue circles represent extinct haplotypes. (A)AChE2 haplotype genealogy based on the portion before the recombination breakpoint recovered by GARD, (B)AChE2 haplotype genealogy based on the portion after the recombination breakpoint. Haplotype numbers refer to the AChE2 haplotypes based on the whole sequences. Haplotypes that lack the S291G mutation are shown in bold. (C) Haplotype genealogies for DP1 and (D) for JHE-b sequences.
Piiroinen et al. BMC Evolutionary Biology 2013 13:13 doi:10.1186/1471-2148-13-13