Significant variation in the number of overlapping gene pairs of A. aegypti and A. gambiae based on presence or absence of orthology in D. melanogaster genome. Y-axis shows number of gene pairs and x-axis shows whether the pairs have or don’t have orthology of A. aegypti and A. gambiae genes in the D. melanogaster genome. The p-value shows significance by Chi square test. It shows that the ancestral genes (where orthology is evident in D. melanogaster) are comparable in numbers between A. aegypti and A. gambiae whereas the young gene pairs vary significantly between the two species suggesting that the young genes are major contributors to the positional overlapping among genes.
Behura and Severson BMC Evolutionary Biology 2013 13:124 doi:10.1186/1471-2148-13-124