Evolution of the dynactin complex with respect to the yeast species evolution. The phylogenetic tree of the Saccharomycetes and Schizosaccharomycetes is based on the Maximum-Likelihood tree (RAxML) of the concatenated dynactin2, Cap1, Cap2, Arp1, and Arp10 subunits. Bootstrap support values (100 randomisations) are given for every node. The phylogenetic distribution of the sampled species is in overall agreement with other recent yeast phylogenies [106,107]. Small differences are most likely due to the different genes (LSU rRNA, SSU rRNA and EF-1α DNA sequences in , 542 putative orthologous proteins in , and dynactin protein sequences in our analysis) and methods used (NJ and MP in , ML in  and in our analysis). On the left the phylogenetic tree is shown with the corresponding species at each leaf. White boxes at branches represent gene loss events. On the right those subunits of the dynactin complex are tabulated that show differential inclusion within the analysed species. Dynactin subunits that are present in all species have been omitted for clarity. The abbreviation ‘n’ denotes the absence of the corresponding subunit in the respective genome while blanks indicate their presence.
Hammesfahr and Kollmar BMC Evolutionary Biology 2012 12:95 doi:10.1186/1471-2148-12-95