Open Access Research article

Exploring the evolution of protein function in Archaea

Alexander Goncearenco12 and Igor N Berezovsky1*

Author Affiliations

1 Computational Biology Unit, Uni Research, University of Bergen, N-5008, Bergen, Norway

2 Department of Informatics, University of Bergen, N-5008, Bergen, Norway

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BMC Evolutionary Biology 2012, 12:75  doi:10.1186/1471-2148-12-75

Published: 30 May 2012

Additional files

Additional file 1:

Contains the complete lists of SCOP folds found in the core, shell, and orphans groups of arCOGs, as well as in the intersections between the groups.

Format: XLS Size: 68KB Download file

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Additional file 2:

Contains the logo representation of the sequence profiles of elementary functional loops.

Format: PDF Size: 7.3MB Download file

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Additional file 3:

Contains description of enzymes involved in methanogenesis, the list of the corresponding arCOGs (Additional file3: Table S1), and the graphs of connections between methanogenic arCOGs (Additional file3: Figure S1) and the domains comprising them (Additional file3: Figure S2) [[29],[35],[58-61]].

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Open Data

Additional file 4:

Contains the list of archaeal proteomes used to obtain sequence profiles.

Format: PDF Size: 74KB Download file

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Open Data