Email updates

Keep up to date with the latest news and content from BMC Evolutionary Biology and BioMed Central.

Open Access Highly Accessed Research article

Balancing selection and genetic drift at major histocompatibility complex class II genes in isolated populations of golden snub-nosed monkey (Rhinopithecus roxellana)

Mao-Fang Luo123, Hui-Juan Pan4, Zhi-Jin Liu1 and Ming Li1*

Author Affiliations

1 Key laboratory of Animal Ecology and Conservation Biology, Institute of Zoology, Chinese Academy of Sciences, 1-5 Beixhenxi Road, Chaoyang, Beijing, 100101, China

2 Key Laboratory of Vegetation and Environmental Change, Institute of Botany, Chinese Academy of Sciences, Beijing, 100093, China

3 Graduate School of the Chinese Academy of Sciences, Beijing, 100049, China

4 College of Nature Conservation, Beijing Forestry University, Beijing, 100083, China

For all author emails, please log on.

BMC Evolutionary Biology 2012, 12:207  doi:10.1186/1471-2148-12-207

Published: 19 October 2012

Additional files

Additional file 1:

Table S1. Microsatellite data of 64 samples.

Format: DOC Size: 395KB Download file

This file can be viewed with: Microsoft Word Viewer

Open Data

Additional file 2:

Table S2. MHC haplotype distributions in populations.

Format: DOC Size: 50KB Download file

This file can be viewed with: Microsoft Word Viewer

Open Data

Additional file 3:

Figure S1. Median-joining networks for MHC alleles of the snub-nosed monkeys. A) Network for DQA1 alleles; B) Network for DQB1 alleles. The circles represent alleles (SG population-red, QL population-yellow, SNJ population-blue), with the area proportional to the frequency of the alleles in the 3 populations.

Format: DOC Size: 88KB Download file

This file can be viewed with: Microsoft Word Viewer

Open Data

Additional file 4:

Table S3. Alignment of the deduced amino acid sequences of Rhro-DQA1 exon 2 sequences. Identical amino acids are shown by points, * represent ABS site, and sites revealed to be under significant selection in PAML are shown by dash.

Format: DOC Size: 37KB Download file

This file can be viewed with: Microsoft Word Viewer

Open Data

Additional file 5:

Table S4. Alignment of the deduced amino acid sequences of Rhro-DQB1 exon 2 sequences. Identical amino acids are shown by points, * represent ABS site, and sites revealed to be under significant selection in PAML are shown by dash.

Format: DOC Size: 40KB Download file

This file can be viewed with: Microsoft Word Viewer

Open Data

Additional file 6:

Table S5. cDNA primer sets for DQA and DQB (primer sets with * were those that amplified successfully in cDNA). Their location within the gene is shown in Additional file 7: Figure S2.

Format: DOC Size: 35KB Download file

This file can be viewed with: Microsoft Word Viewer

Open Data

Additional file 7:

Figure S2. Schematic representation of the position of cDNA primer sets used in the study of MHC II variation.

Format: DOC Size: 37KB Download file

This file can be viewed with: Microsoft Word Viewer

Open Data