|Phylogenetic signal in chemistry and biological activity determined using Fritz and Purvis’sDmetric (see Materials and Methods for details)|
|a) Chemical components|
|Alkaloid group||D||P (D = 1)||P (D = 0)|
|b) Biological activity|
|Measure||D||P (D = 1)||P (D = 0)|
D is equal to 1 if the observed chemical component has a random distribution (i.e. no phylogenetic signal). D is equal to 0 if the component is distributed exactly as would be predicted under a Brownian motion model of gradual divergent evolution (i.e. strong phylogenetic signal). P values represent the probability that the observed D value is equal to 1 or 0, respectively (P >0.05 indicates that the observed value is not significantly different from these values).
Rønsted et al.
Rønsted et al. BMC Evolutionary Biology 2012 12:182 doi:10.1186/1471-2148-12-182