Table 2

Phylogenetic signal in chemistry and biological activity determined using Fritz and Purvis’s[57]Dmetric (see Materials and Methods for details)
a) Chemical components
Alkaloid group D P (D = 1) P (D = 0)
Crinine 0.6768 0.021 0
Galanthamine 0.549 0 0.009
Lycorine 0.77 0.018 0
Galanthindole 1.091 0.621 0.011
Homolycorine 0.769 0.021 0
Montanine 0.572 0.002 0.01
Tazettine 0.852 0.094 0
b) Biological activity
Measure D P (D = 1) P (D = 0)
AChE 0.679 0.004 0.001
SERT 0.634 0.037 0.044

D is equal to 1 if the observed chemical component has a random distribution (i.e. no phylogenetic signal). D is equal to 0 if the component is distributed exactly as would be predicted under a Brownian motion model of gradual divergent evolution (i.e. strong phylogenetic signal). P values represent the probability that the observed D value is equal to 1 or 0, respectively (P >0.05 indicates that the observed value is not significantly different from these values).

Rønsted et al.

Rønsted et al. BMC Evolutionary Biology 2012 12:182   doi:10.1186/1471-2148-12-182

Open Data