Table 5

Enriched biological process GOa terms in protein families died at the LCAsb of three major metazoan groups
Groups GO terms Description P-value
Families died at the LCA of arthropods
GO:0006637 acyl-CoA metabolic process 1.75E-18
GO:0030704 vitelline membrane formation 9.07E-18
GO:0006869 lipid transport 2.08E-09
GO:0006814 sodium ion transport 1.81E-08
GO:0045454 cell redox homeostasis 2.84E-08
GO:0006555 methionine metabolic process 4.00E-04
GO:0006952 defense response 5.87E-04
Families died at the LCA of nematodes
GO:0006308 DNA catabolic process 8.53E-08
GO:0006281 DNA repair 7.29E-05
GO:0035023 regulation of Rho protein signal transduction 2.10E-04
GO:0006779 porphyrin biosynthetic process 2.65E-04
GO:0006493 protein amino acid O-linked glycosylation 2.96E-04
GO:0017000 antibiotic biosynthetic process 8.77E-04
Families died at the LCA of vertebrates
GO:0007186 G-protein coupled receptor protein signaling pathway 3.00E-12
GO:0016539 intein-mediated protein splicing 1.00E-07
GO:0007154 cell communication 3.28E-05
GO:0006030 chitin metabolic process 9.21E-05
GO:0006097 glyoxylate cycle 1.83E-04
GO:0007275 multicellular organismal development 1.98E-04

a GO, Gene Onthology; b LCA, Last Common Ancestor.

Wang et al.

Wang et al. BMC Evolutionary Biology 2012 12:138   doi:10.1186/1471-2148-12-138

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