Additional file 2.

Alignment of PSLPINc and hSMG6PINc residues. The protein domain alignment of PSLsPINc and hSMG6PINc is reported showing the conservation of catalytic residues. Dotted lines represent gaps in the alignment. Active sites are labeled with a green octagon when the residues are conserved among PSLsPINc and hSMG6PINc. A yellow or a red octagon mark an aminoacid substitution of same or different polarity, respectively.

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Cigliano et al. BMC Evolutionary Biology 2011 11:78   doi:10.1186/1471-2148-11-78