Representation of the HS1.2 variants in 20 different species. The alignment of the HS1.2 enhancer clones of the different species is shown by schematic representation. The conserved elements from the 5' towards the 3' are: the core constant part of the enhancer (fuchsia), the 29 mer sequence (red), the 40 mer (yellow), the stretch of cytosines (green), and the 3' end region (light blue) (see also Figure 2). The number of 40 mer copies appears variable in most of the primates. In these species the alleles with different number of the 40 mer can harbor either the 29 mer or the cytosine stretch between the core and the first 40 mer. Alleles with the 29 mer are present in the major part of the species. We found only clones with the cytosine stretch at the place of the 29 mer just in Gorilla. The identification number (ID) of each sequence is reported in the second column: the ID including a letter can be found in GenBank http://www.ncbi.nlm.nih.gov/Entrez/ webcite, the others in the Trace Archive database http://www.ncbi.nlm.nih.gov/Traces/trace.cgi webcite. The bold characters are used to indicate sequences obtained in our laboratory.
D'Addabbo et al. BMC Evolutionary Biology 2011 11:71 doi:10.1186/1471-2148-11-71