Table 4

Genetic distance to a new genotype network decreases with increasing penetrance

N

c

d

Spearman's ρ

p-value

8

0.4

0.25

-0.268

< 2.2 × 10^-16

0.125

-0.211

< 2.2 × 10^-16

0.3

0.25

-0.218

< 2.2 × 10^-16

16

0.35

0.25

-0.293

< 2.2 × 10^-16

0.25

0.125

-0.263

< 2.2 × 10^-16

0.25

-0.306

< 2.2 × 10^-16

20

0.3

0.25

-0.26

< 2.2 × 10^-16

0.2

0.1

-0.269

< 2.2 × 10^-16

0.25

-0.33

< 2.2 × 10^-16

0.5

-0.4

< 2.2 × 10^-16

0.1

0.25

-0.23

< 2.2 × 10^-16

Data for each parameter combination is based on 10⁴ different circuits and on the non-parametric rank correlation coefficient Spearman's ρ [76].

Espinosa-Soto et al. BMC Evolutionary Biology 2011 11:5   doi:10.1186/1471-2148-11-5