Table 2

Molecular environment of the substituted sites in Pla structure and Epo model

Pla

Contact

Epo

Contact


MRKX05

K161

solvent

N159

Q160, R161


G162

-

Q160

N159, R161


V163

p160,

    m210

R161

N159, Q160, p158


R164

    y209
, t142

P162

R161


V165

H101, a143, g145, i166

G163

-


MRKX10

K262

    e207
,
    t214

T260

    S210
,
    t212
, d259


N263

    D212
, d261

I261

d259


V268

I270

A266

i257


s269

q258

s267

q256


I270

t257, V268, a274

L268

-


G271

-

D269

a32, g270


Residues whose side chains come within 4 Å of the central amino acid are listed. The amino acids in each loop are indicated in different font styles, L3 (G145-V165) in bold,

    L4 (H208-L213) underlined
and L5 (G255-A274) in italics in Pla numbering.

Residues that are conserved at the site are shown in lower case letters, and the non-conserved ones in capital letters.

Haiko et al. BMC Evolutionary Biology 2011 11:43   doi:10.1186/1471-2148-11-43

Open Data