Exposure of residues to the exterior of the MEPE protein. Plot of the ASA ratio calculated between the side-chain and the 'random coil' value of each residue. Sites with a ratio above 50% (yellow box) are considered to be exposed to the outside of the protein whereas sites under 20% are considered to be buried (pink box). Sites under positive selection in both gene and protein-level analyses are marked with the red dots (double) and sites showing selection in at least one of the analysis is represented as black dots (single).
Machado et al. BMC Evolutionary Biology 2011 11:342 doi:10.1186/1471-2148-11-342