Distribution of changes in complexity (PCPC) fixed during the adaptive process A) 12 populations of size 100 were adapted to an OLP of 4 in three independent replica from 4 networks previously adapted to an OLP of 8 for 10 million generations. The populations were evolved under an "adaptive dynamics" process of adaptation (low mutation rate such that populations were always monomorphic unless a single mutant occurred and got either lost of fixed). The changes in PCPC of all the fixed mutations were then recorded. We focused on changes occurring while fitness of the network population changed from 10% to 60%, to avoid any effect due to the stabilization of the changes in PCPC in early and late phases of adaptation. The red dotted line represents the mean change in PCPC. B) Same as in A with a population size of 10 000. C) Same as in A on 5 networks (in 5 replicates each) adapting from an OLP of 4 to an OLP of 8 with a population of 100. Changes in PCPC were recorded while fitness changed from 5% to 30%. D) Same as in C with a population size of 10 000.
Le Nagard et al. BMC Evolutionary Biology 2011 11:326 doi:10.1186/1471-2148-11-326