Gene structures of alternatively spliced coronins. The cartoons outline the gene structures of the alternatively spliced coronin-1 gene from Caenorhabditis elegans, CeCoro1, and the coronin-1D gene from Homo sapiens, HsCoro1D. The alternatively spliced CeCoro1 gene contains a differentially included exon8, which has an additional alternative 3'-splice site, leading to three transcripts. The other two described splice sites, an alternative 3'-splice site of exon7 and an alternative 5'-splice site of exon8 , are most probably artificial. The HsCoro1D gene contains a cluster of two mutually exclusive spliced exons, exon5a and exon5b, and an alternative 5'-splice site of exon10. Dark grey bars and light grey bars mark exons and introns, respectively, and alternative exons and splice sites are coloured.
Eckert et al. BMC Evolutionary Biology 2011 11:268 doi:10.1186/1471-2148-11-268