Open Access Research article

A holistic phylogeny of the coronin gene family reveals an ancient origin of the tandem-coronin, defines a new subfamily, and predicts protein function

Christian Eckert, Björn Hammesfahr and Martin Kollmar*

Author Affiliations

Department of NMR-based Structural Biology, Max-Planck-Institute for Biophysical Chemistry, Am Fassberg 11, 37077 Goettingen, Germany

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BMC Evolutionary Biology 2011, 11:268  doi:10.1186/1471-2148-11-268

Published: 25 September 2011

Additional files

Additional file 1:

Sequence alignment of the coronins The file contains the alignment of the full-length sequences of the coronins in fasta-format. The data can also be downloaded from CyMoBase [61].

Format: ZIP Size: 173KB Download file

Open Data

Additional file 2:

MrBayes tree of the coronin family This file contains the phylogenetic tree calculated with MrBayes including posterior probability values that has been the basis for Figure 1. Here, the tree is plotted in an extended way so that every coronin can be found and compared easily.

Format: PDF Size: 400KB Download file

This file can be viewed with: Adobe Acrobat Reader

Open Data

Additional file 3:

RAxML tree of the coronin family This file contains the phylogenetic tree calculated with RAxML including bootstrap values. The tree is plotted in an extended way so that every coronin can be found and compared easily.

Format: PDF Size: 6.9MB Download file

This file can be viewed with: Adobe Acrobat Reader

Open Data

Additional file 4:

Coronin repertoire of all eukaryotes analyzed Complete table of the coronin inventories of 358 eukaryotes.

Format: PDF Size: 160KB Download file

This file can be viewed with: Adobe Acrobat Reader

Open Data

Additional file 5:

Conserved residues in the coronin domain This figure contains the sequence conservation of the entire coronin domain including all mutagenesis experiments as described in Cai et al. [40] and Gandhi et al. [41].

Format: PDF Size: 223KB Download file

This file can be viewed with: Adobe Acrobat Reader

Open Data