Table 3

Physical distances between residue pairs

Species

Rubisco state

PDB

3D-distance

Coevolving sites distance

Positively selected sites distance

Positively selected site/active site distance


mean

median

st.dev.

mean

median

p-value#

Difference*

mean

median

p-value#

Difference*

mean

median

p-value#

Difference*


Nicotiana tabacum

Activated

4RUB

31.38

29.66

14.34

28.14

26.66

6.7E-9

(1.8E-8)

3.24

33.76

31.97

0.057

(0.036)

2.38

28.50

26.23

0.144

(0.164)

2.88


Unactivated

1EJ7

31.44

29.86

14.24

27.5

25.6

5.6E-10

(6.9E-10)

3.94

33.01

32.40

0.146

(0.094)

1.57

27.97

25.28

0.099

(0.126)

3.47


Average minimum

28.76

27.13

13.58

25.27

22.77

1.8E-8

(6.1E-9)

3.50

31.55

30.27

0.025

(0.019)

2.78

26.18

24.02

0.156

(0.192)

2.59


Spinacia oleracea

Activated

8RUC

31.48

29.77

14.37

28.21

26.56

1.1E-8

(1.3E-8)

3.27

34.15

32.08

0.038

(0.025)

2.62

28.74

26.38

0.156

(0.181)

2.74


Unactivated

1RCX

31.24

29.54

14.26

27.97

26.23

8.5E-9

(1.1E-8)

3.27

33.97

32.12

0.034

(0.022)

2.73

28.51

26.09

0.155

(0.180)

2.73


Average minimum

31.22

29.53

14.26

27.96

26.23

9.3E-9

(8.2E-9)

3.26

33.94

32.08

0.034

(0.023)

2.72

28.50

26.09

0.156

(0.180)

2.72


*The mean difference between the values of the 3D distance with the corresponding distance.

# p-values as calculated from one sample Z-test and, in parentheses, from the Wilcoxon Rank Sum Rank Test.

Wang et al. BMC Evolutionary Biology 2011 11:266   doi:10.1186/1471-2148-11-266

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