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Open Access Highly Accessed Research article

Evolutionary versatility of eukaryotic protein domains revealed by their bigram networks

Xueying Xie1*, Jing Jin2 and Yongyi Mao3*

Author Affiliations

1 Research Center for Learning Science, Southeast University, Sipai Lou 2, Nanjing 210096 China

2 Centre for systems Biology, Samuel Lunenfeld Research Institute, Mount Sinai Hospital, 600 University Avenue, Toronto, Ontario M5G 1X5 Canada

3 School of Information Technology and Engineering (SITE), University of Ottawa, Ottawa, Ontario, K1N 6N5 Canada

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BMC Evolutionary Biology 2011, 11:242  doi:10.1186/1471-2148-11-242

Published: 18 August 2011

Additional files

Additional File 1:

supplementary results, tables and figures. supplementary results, tables (Table S1, S2) and figures (Figure S1, S2, S3, S4, S5, S6, S7, S8)

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Additional File 2:

The survey information of domains in four kingdoms. common domains shared by all genomes (Table S1) and specific domains found in each kingdom (Table S2, S3, S4).

Format: XLS Size: 68KB Download file

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Additional File 3:

The dependence of clustering coefficient on node degree in the 77 domain bigram networks. The log-log plots of clustering coefficient versus the degree of node in networks.

Format: PDF Size: 3.3MB Download file

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