GPRC5 genes are regulated by vitamin A. (A) Schematic representation of the generation of vitamin A-deficient mice (VitA-). (B) Quantitative PCR analysis of GPRC5 mRNA expression levels in lung (GPRC5A) and in whole brain lysates (GPRC5B and GPRC5C). GPRC5B mRNA was significantly reduced in vitamin A deficient mice (n = 5 animals), whereas GPRC5C and GPRC5A mRNAs showed only a non-significant reduction compared to non-treated wt mice (n = 5 animals). Error bars represent SEM.
Kurtenbach et al. BMC Evolutionary Biology 2011 11:234 doi:10.1186/1471-2148-11-234