Figure 1.

Hypotheses of mtMutS origins. Three previously-proposed hypotheses concerning the proximate origins of octocoral mtMutS. (A) mtMutS originated as a nuclear MSH gene and was subsequently transferred to the mitochondrial genome in octocorals [15]; (B) mtMutS entered the ancestral eukaryotic cell via endosymbiosis of the mitochondrion-like bacterial ancestor, and was subsequently transferred to the nucleus as MSH and lost from the mitochondrion of all other eukaryotes [18]; (C) Although both involved a bacterial MutS precursor, mtMutS was acquired by the ancestral octocoral mitochondrion independent of the means by which eukaryotic nuclei acquired MSH [32].

Bilewitch and Degnan BMC Evolutionary Biology 2011 11:228   doi:10.1186/1471-2148-11-228
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